During the film, CIA detective Reed is investigating a series of mysterious crimes which he believes are connected to the elusive Chronos Corporation. His investigation does not go well as he is repeatedly blocked by his superiors, who insist that Chronos have nothing to do with any of these unusual crimes. What Max doesn't know is that there are members of the CIA on Chronos' payroll who are intentionally trying to stop him from revealing the company's illegal genetic research.
After discovering the body of Dr. Tetsu Segawa, Max informs the doctor's daughter Mizky of her father's fate. From then on, he keeps close tabs on her and her boyfriend Sean Barker in the certainty that they might lead him to the Guyver, an alien device that was stolen from Chronos by Dr. Segawa before his death.
Both Sean and Max intrude upon Chronos' attempted kidnapping of Mizky and try to save her, with Sean revealing himself as being the host of the Guyver. He fights against Lisker and the Zoanoids, but his lack of combat skill leads to him getting killed and both Mizky and Max getting captured.