Another version of Jackie lived in the parallel universe that the Tenth Doctor visited during the episodes "Rise of the Cybermen" and "Age of Steel". In this world, she and her husband Peter lived a life of wealth and luxury thanks to Peter's successful business deals (which all failed miserably back in the prime universe). Though they remained married and lived an ideal lifestyle, the Tylers never had children, though Jackie did have a dog which she named "Rose".
When John Lumic attempted to convert London's population into Cybermen, he transmitted a mind-control signal to every EarPod in the city. Jackie also wore a pair of EarPods and was affected by the signal, marching into the Cybus factory in Battersea and undergoing conversion. Peter and Rose infiltrated the factory to try and find her, but they were approached by a Cyberman which revealed itself to have once been Jackie. Pete was horrified and outraged, but expressing this blew his cover and he and Rose were captured and taken to Cyber Control where they faced the upgraded Lumic. When the Doctor shut off the Cybermen's emotional inhibitors, all of the Cybermen, including Jackie, went insane and began to malfunction and self-destruct.