Brenda Gutierrez is a supporting character in the comedy-horror film Slither. In her youth, she and Grant Grant were going steady, but Grant would later marry Starla and Brenda found herself a new man with whom she had a child. After Grant became infected by a parasitic alien organism, he made advances on Brenda in order to make her a breeder. She was portrayed by Brenda James.
In her youth, Brenda Montgomery was involved with Grant Grant, but after Grant went to university the two drifted apart. During the film's events, Brenda - now married under the surname Gutierrez - lives an ordinarily banal life with her husband and infant son. One night, she meets Grant once again at a bar. The both of them are sexually frustrated which leads to a brief affair in the pastures on the edge of town. It is then that Grant discovers a mysterious slug-like creature in the tall grass which shoots some kind of needle into his chest. Brenda runs off to find help, but returns later to find Grant is gone, having returned home.
Two nights later, Grant visits Brenda's house. Brenda thinks that Grant wants to pick up where they left off, but when Grant takes off his shirt, she is horrified to find two strange tentacles extending from a hole in his chest. The mutated Grant pins Brenda down and essentially rapes her, planting his tentacles into her stomach to convert her into a breeder for his parasitic offspring.
Days later, after Grant's involvement in several animal killings has been confirmed, Chief Bill Prady rounds up a posse to find Grant and the missing Brenda. Their search leads them to an isolated barn in the woods where they find Brenda, whose body has swollen up to absurd proportions. Having been turned into a breeder, Brenda is endlessly hungry and Grant has been feeding her a steady supply of live meat to sustain the massive clutch of worms developing inside her. Bill, Starla and the other posse members watch in horror as the worms inside Brenda rip her apart from the inside out and slither away into the night in search of hosts.